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MMAD (Demethyldolastatin 10)

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SKU: 203849-91-6. Category:

AASraw waxaa ku jira awoodda wax soo saar iyo karti wax-soo-saarka laga bilaabo gram ilaa amarka xajmiga MMAD (Demethyldolastatin 10) (CAS 203849-91-6), iyada oo la raacayo Xeerarka CGMP iyo nidaamka kantaroolka tayada la socon karo.

Intaa waxaa dheer, MMAD waxaa lagu soo waramayaa in loo isticmaalo soo saarida daawooyinka isku-dhafan ee antibody (NDCs). Gudaha NDC-yada, MMAD waxaa lagu daraa antibiyootka anti-5T4 ama antibio-anti-Her2. Waxaa la muujiyey in NDCs muujiyaan waxtarka wanaagsan iyo farmasokokinetics.

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Product Description

MMAD (Demethyldolastatin 10) video


MMAD (Demethyldolastatin 10) Calaamadaha aasaasiga ah

Name: MMAD (Demethyldolastatin 10)
CAS: 203849-91-6
Formula kelli: C41H66N6O6S
Miisaankani waa: 771.06
Dhibcaha Biyaha: N / A
Kaydinta Nabadgelyada: Powder-20 ° C 3 sano
4 ° C 2 sano
Xalka -80 ° C 6 bilood
-20 ° C bisha 1
Color: Caddaan si cad-cad (adag)


MMAD (Demethyldolastatin 10) (203849-91-6) isticmaalka wareegga steroid

Names

Tusaale ahaan: Demethyldolastatin 10 (203849-91-6); Monomethylauristatin D; Monomethyl Dolastatin 10
Chemical Name: (S)-N-((3R,4S,5S)-3-methoxy-1-((S)-2-((1R,2R)-1-methoxy-2-methyl-3-oxo-3-(((S)-2-phenyl-1-(thiazol-2-yl)ethyl)amino)propyl)pyrrolidin-1-yl)-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamide

Digniin ku saabsan MMAD (Demethyldolastatin 10)

Alaabta aan si buuxda loo ansixin codsiyada caafimaadka. Isticmaalka cilmi baarista kaliya

Si aad u heshid xakameyn sare, fadlan diirada tuubada 37 ℃ oo ruxin bacda ultrasonic mudo ah. Qalabka xakamaynta waxaa lagu kaydin karaa hoos -20 ℃ dhawr bilood.

Tilmaamo kale

In Vitro: MMAD (Demethyldolastatin 10) (203849-91-6) waxay ku xiran tahay geeddi-socodka xasaasiga ah ee xasilinta si ay u keento isku-dhowaansho-isku-dhafan oo isugu jira daawooyinka antibody-drug antibody (ADCs) oo leh saamiga daroogada-ilaa-antibody ee ~ 2.0. Unugugyada soo baxay waxay muujiyaan guryaha farmasokinetic wanaagsan, firfircoon ee ficil-celinta cytotoxic ah oo ka dhan ah HER2 + unugyada kansarka. Marka la barbardhigo ADC-yada loo diyaariyay by alkylation cysteine ​​ka dib markii la yareeyo disulfide ku-dhalashada interscain, ADCs-ku-salaysan aan-ahayn-amino-acid-ku salaysan goobta waxaa lagu muujiyay in ay kordheen in vitro cytotoxicity

Vivi: Isugeynta daawooyinka antibody-ka ee (ADCs) waxay muujinayaan qanjidhada buuxda ee jiirka. Waxa kale oo ay leeyihiin hindhisada fiicnaanta sunta ee jiirka.


Sida loo iibsado MMAD; iibso Demethyldolastatin 10 ka soo AASraw

1.To nagula soo xiriir emailkayaga nidaamka weydiinta, ama skype onlinewakiil adeegga macaamiisha (CSR).
2.To nuujinta tirada iyo cinwaanka aad weydiisatay.
3.Our CSR waxay ku siin doontaa qiimaha, qiimaha bixinta, nambarka raadinta, siyaabaha gudbinta iyo taariikhda la qiyaasi karo (ETA).
4.Payment ayaa la sameeyaa, alaabtana waxaa loo diri doonaa saacadaha 12 (Si loo dalbado 10kg).
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