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Budada Lapatinib (231277-92-2)

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5.00 ka mid ah 5 ku saleysan 1 macaamiisha rating
SKU: 231277-92-2. Category:

AASraw waxaa ku jira awoodda wax soo saar iyo karti wax-soo-saarka laga bilaabo gram ilaa nidaamka xajmiga ee budada Lapatinib (231277-92-2), iyada oo la raacayo Xeerarka CGMP iyo nidaamka kantaroolka tayada la socon karo.

Product Description

Fiidiyowga Lapatinib video


Budada Lapatinib Calaamadaha aasaasiga ah

Name: Budada Lapatinib
CAS: 231277-92-2
Formula kelli: C29H26ClFN4O4S
Miisaankani waa: 581.05
Dhibcaha Biyaha: 136-140 ° C
Kaydinta Nabadgelyada: qaboojiyaha
Color: Caddaan cad ama midab cad oo budada ah


Root Lapatinib budada ee wareegga Agentoplastic Agentoplastic

Names

Magaca Guud: Dufanka Lapatinib (La PA)
Magaca Calaamadda: Tykerb

Isticmaalka budada Raw Lapatinib

Kiniiniga Lapatinib waa dawo rijeeto oo loo isticmaalo dawo kale (capcitabine) si loogu daaweeyo dadka qaba kansarka naasaha oo ku faafay meelo kale oo jirka ka mid ah oo HER2 positive (burooyin oo soo saaro qadar badan oo boroti ah oo loo yaqaan 'epidermal growth factor receptor-2) , iyo kuwa hore u lahaa daaweyn kansarka naasaha kale ah.

Daawada Lapatinib waxaa sidoo kale loo isticmaalaa nooc daawo ah oo loo yaqaan 'letrozole' oo loogu talagalay daaweynta haweenka postmenopausal oo leh hormoonka hormoonka haboon, HER2 oo leh kansar naas nuujin ah oo loogu talagalay daaweyn hormoon ah.

Budada Lapatinib waa dawo rijeeto loo isticmaalo daaweynta kansarka naasaha. Waxaa loo isticmaalaa daawooyinka kale si loo daaweeyo nooc ka mid ah kansarka naasaha oo ku faafay qaybaha kale ee jidhka oo aan ka jawaabin daweynta kansarka kale.

Daawada Lapatinib waxaa ka mid ah koox daawooyinka loo yaqaan 'kinase inhibitors' kaas oo ka shaqeynaya joojinta ficilka borotiinka qaarkood oo muujiya unugyada kansarka si loo badiyo.

Dawadani waxay ku dhacdaa qaab kiniin ah waxaana la qaadaa hal mar maalin calool madhan.

Waxyeellooyinka caamka ah ee ka yimaada budada Lapatinib waxaa ka mid ah casaan, gacmo iyo lugo xanuun, shuban, firiiric, iyo lallabo.

Waa maxay qiyaasta budada Lapatinib

Qiyaasta Cudurka Qaaxada ee caadiga ah ee Kansarka Naasaha

-HER2-POSITIVE MEDASTATIC BREAST CANCER (oo ay la socoto xarfantin): 1250 mg halkiiba hal jeer maalintii Maalmaha 1 ee 21 si joogto ah ugu soo noqnoqonaya wareegyada 21-maalmood ilaa illaa cudurada ama sunta aan la aqbali karin.

-HORMONE RECEPTOR-POSITIVE, HER2-POSITIVE NAFAQADA KONTOROOLKA KANSARKA (oo ay la socdaan haemoszole): 1500 mg afka ah hal mar maalintii.

Comments:
-Ku dar siinta macluumaadka soo saaraha wax soo saarka ee loo yaqaan capecitabine iyo talooyinka loo yaqaan 'letrozole'.
-HER2-oof-wareerka ku salaysan naas-nuujinta naas-nuujinta bukaanka waa in ay yeeshaan xanuunka trastuzumab ka hor inta aan la bilaabin daaweynta daroogada taas oo ay weheliso capecitabine.

Wuxuu isticmaalaa:
-In la isku daro capecitabine ee daaweynta bukaanka qaba kansarka naasaha ee sareeya ama sareeya ee burkoodu uu aad u sarreeyo HER2 iyo kuwa helay daaweynta hore oo ay ku jiraan anthracycline, taxane, iyo trastuzumab.
-In la isku daro haistozole oo loogu talagalay daaweynta haweenka postmenopausal oo leh hormoonka hormoonka-naas-nuujinta kansarka naas-nuujinta oo si weyn u xoojiya daaweeye HER2 oo loogu talagalay daaweynta hoormoonka daaweynta.

Isbedelada Qiyaasta "Renal Dose"
Xogta aan la heli karin oo ku saabsan qiyaasta qiyaasta; Si kastaba ha ahaatee, farmasokokinetics-ka daawadani uma badna in ay saameyn ku yeeshaan taas oo ka yar 2% qiyaasta daawada la karkariyo kelyaha.

Isbedelada Qaadashada Beerka
MILKU DHACAYA MUSTAQBALKA HEPERTIINTA HEPATALKA (CARRUURTA AAN BUUXINTA A / B): Macluumaadka aan la heli karin.

KA HORTAGIDDA CUDURRADA HEPE (CUNTADA-CUDUR C): Iska yaree qiyaasta:
-HER2-Kansar Kacsan ee Kansarka Naasaha (oo lagu daro capecitabine): 750 mg / maalin.
-Hormo-Dib-u-daweenta-Horumar, HER2-Kacsan ee Kansarka Naas-nuujinta (oo laysku geeyo haayrozole): 1000 mg / maalin

MACLUUMAADKA KA HORTAGISTA CUDURADA DHALINYARADA: Si joogta ah u jooji daaweynta.

Faallooyinka: Talooyinka hagaajinta qiyaasta waxay ku saleysan yihiin daraasadaha daawooyinka farmashiyaha; ma jiraan xog caafimaad oo la heli karo.

Dejinta Qaadashada
KALA-XIRIIRKA ISTICMAALKA ISTICMAALKA CYP450 3A4 IYO / AMA CALAAMADAHA CUDURKA 450A3: Ka fogow isticmaalka wadajirka ah haddii ay macquul tahay. Talooyinka hagaajinta qiyaasta ah waxay ku saleysan yihiin daraasadaha daawooyinka farmashiyaha; ma jiraan xog caafimaad oo la heli karo.
XADIISKA ISTICMAALKA CUDURRADA 450A3 INHIBITOR: Iska yaree xaddiga 4 mg / maalin; u ogolow muddada isgaadhsiinta ee qiyaastii 500 ka hor inta aan la isku dhejin daawadaas qiyaasta talada caadiga ah haddii daaweenta la joojiyo.
XADIISKA ISTICMAALKA QALABKA CYP450 3A4 INDUCER: Qadarka kor u kaca ee titrate ku salaysan dulqaad; hoos u dhigista qiyaasta daawada ee lagu taliyey haddii daaweenta la joojiyo.
-HER2-Kansarka Naas-nuujinta leh ee Kansarka Naasaha (oo ay weheliso capecitabine): Kordhiya qiyaasta xmUMX mg / maalin.
-Hormo-Dib-u-daweenta-Horumar, HER2-Kacsan ee Kansarka Kansarka Naasaha (oo lagu daro letrozole): Kordhiya qiyaasta xmUMX mg / maalin.

GRADE 2 ama BADBAADEEDA LAGU QAADO LABA DHEXE LABA DHIBAATOOYINKA LAGU HESHIISO AMA LAGU QAADO DARAASKA SOO BANDHIGIDA DHALINYARADA NORMALKA: Jooji daaweynta; waxaa laga yaabaa in uu dib u bilaabo qiyaasta la yareeyey ka dib ugu yaraan toddobaadyada XNUM haddii LVEF ay soo kabato caadi ahaan iyo bukaanku waa asymptomatic.
Qiyaasaha La Yareeyey:
-HER2-Kansarka Kansarka leh ee Kansarka Naasaha (oo lagu daro capecitabine): 1000 mg / maalin
-Hormo-Dib-u-daweenta-Horumar, HER2-Kacsan ee Kansarka Naas-nuujinta (oo laysku geeyo haayrozole): 1250 mg / maalin

MAGAALADA 3 AMA DHAMMAAN 1 ama 2 DIARRHEA ILAALINTA QIIMEYNTA (qallooca dhexdhexaad iyo caloosha oo daran, Qalabka 2 ama lallabo ama matag badan, xaaladda hoos u dhaca, qandhada, sepsis, nutropenia, dhiig baxa, ama fuuqbax): Waxaa laga yaabaa inay dib u bilaabaan qadar yar marka shuban xallineysaa 1 ama ka yar.
Qiyaasaha La Yareeyey:
-HER2-Bukaanka Naas-Nuujinta Kacsan ee Kansarka ah (oo ay weheliso capecitabine): 1000 mg / maalin
-Hormo-Dib-u-daweenta-Hawl, HER2-Maqnaanshaha wanaagsan ee kansarka naasaha ee bukaanada: 1250mg / maalin
GRADE 4 DIARRHEA: Si joogta ah u jooji daaweynta.

WAXYAABAHA WAX-KA-QAADASHADA, MAGAALADA 2 ama DADKA: Waxaa laga yaabaa inay ka fikirto joojinta ama joojinta qiyaasta; waxaa laga yaabaa in uu dib u bilaabo qiyaasta caadiga ah ee lagu taliyey marka suntu ay hagaagto heerka 1 ama ka yar.
HADDII DAAWEYNTA KHATARAHA: Iska yaree qiyaasta:
-HER2-Kansarka Kansarka leh ee Kansarka Naasaha (oo lagu daro capecitabine): 1000 mg / maalin
-Hormo-Dib-u-daweenta-Hawl, HER2-Maqnaanshaha wanaagsan ee kansarka naasaha ee bukaanada: 1250mg / maalin

Sidee buu u shaqeeyaa budada Lapatinib?

Budada Lapatinib waxaa loo isticmaalaa capecitabine (Xeloda) si loogu daaweeyo nooc ka mid ah kansarka naasaha ee hore ee dadka horey loogu daaweeyey daawooyinka kale ee kemotherabi. Budada Lapatinib waxay ku jirtaa nooc daawo ah oo loo yaqaan 'kinase inhibitors'. Waxay ka shaqeysaa joojinta ficilka borotiinka aan caadiga ahayn ee calaamadaha unugyada kansarku ku dhufanayaan. Tani waxay caawisaa joojinta ama gaabinta faafidda unugyada kansarka.

Digniin

U sheeg dhammaan bixiyeyaashaada daryeelka caafimaadka in aad qaadato budada Lapatinib. Tan waxaa ka mid ah takhaatiirta, kalkaaliyayaasha, farmashiistaha, iyo dhakhaatiirta ilkaha.
Haddii aad caloosha ku xanuunto, tuurto, saxaro dabacsan (shuban), ama aanad gaajoon, la hadal dhakhtarkaaga. Waxaa jiri kara siyaabo lagu yareeyo waxyeelooyinkaas.
Saxaro dabacsan (shuban) ayaa ku dhacay budada Lapatinib. Mararka qaarkood, shubanka aad ayuu u xunaa, dhimashaduna way dhacday. Kala hadal dhakhtarkaaga.
Haddii aad leedahay saxaro dabacsan (shuban), la hadal dhakhtarkaaga. Ha isku dayin inaad daaweyso shubanka adiga oo aan marka hore hubin dhakhtarkaaga.
Shaqada dhiigga hubi sida dhakhtarku kuu sheegay. Kala hadal dhakhtarka.
Waxaad ubaahnaan doontaa baaritaanka wadnaha ee wadnaha adoo qaadanaya budada Lapatinib. Kala hadal dhakhtarka.
Iska ilaali digaagada iyo cabitaanka rootiyada.
Haddii aad qaadatid digoxin, la hadal dhakhtarkaaga. Waxaa laga yaabaa inaad u baahato inaad shaqadaada dhiiggaaga si fiican u hubiso intaad qaadaneyso budada Lapatinib.
Daawadani waxay u keeni kartaa cunuga aan dhalan haddii aad qaadato inta aad uurka leedahay.
Isticmaal xakameynta dhalmada oo aad ku kalsoon tahay si looga hortago uurka inta aad qaadaneysid budada Lapatinib.
Haddii aad uur leedahay ama aad uur leedahay adigoo qaadanaya budada Lapatinib, wac dhakhtarkaaga si sax ah.

Lapatinib Root Powder

Si aad u dalbato 10grams.
Baadhitaanka xaddiga caadiga ah (1kg gudaheeda) waxaa loo diri karaa saacadaha 12 kadib bixinta.
Amar wayn ayaa loo diri karaa 3 maalmaha shaqada ka dib bixinta.

Suuq-geynta Lapatinib Sale

Si loo bixiyo mustaqbalka soo socda.

Miyuu qoyan yahay Lapatinib-ga wax saameyn ah leh

Ayadoo la raacayo saameyntiisa loo baahan yahay, budada Lapatinib waxay keeni kartaa saameyn aan la rabin. Inkastoo aaney dhammaan dhibaatooyinkan daaweyntu dhici karaan, haddii ay dhacaan waxay u baahan yihiin daryeel caafimaad.

Si dhakhso leh u hubi dhakhtarkaaga haddii mid ka mid ah waxyeelooyinka soo socda ay ku dhacaan markaad qaadanayso budada Lapatinib:

Waxyaabaha aan caadi ahayn
Dhibaato ama neefsasho ku shaqeynaya
suuxdin
wadna garaacid ama aan joogto ahayn
shuban daran
xoojinta xabadka
daal aan caadi ahayn ama daciifnimo
Rare

Xanuun ama calool xanuun ama calool xanuun
dhoobo saxaro ah
Kaadi madow
cunto xumo
qandho
madax
cuncun ama finan maqaarka ah
lumitaanka rabitaanka cuntada
lallabbo iyo matagid
bararka cagaha ama lugaha hoose
indhaha ama maqaarka
Xaalad aan la ogeyn
Qalabaynta, diirka, loosinta maqaarka
laab xanuun
qarqaryo
qufac
shuban
Dhibaato liqid
dawakhaad
dareenka guud ee raaxada ama jirrada
finan
xanuun ama murqo xanuun
duufaanka ama bararka indhaha ama indhaha, wajiga, dibnaha, ama carrabka
Dhibaatooyinka maqaarka guduudan, badanaa leh xarun madow
casaan, indho xanaaq
cune xanuun
nabarrada, boogaha, ama dhibco cad oo afka ama bushimaha
xajinta dheecaanka maskaxda
Dhibaatooyinka qaarkood ee ka yimaada budada Lapatinib ayaa dhici karta in badanaa uma baahna daryeel caafimaad. Dhibaatooyinkan ayaa laga yaabaa inay baxaan inta lagu jiro daaweynta marka jidhkaaga uu daaweynayo daawada. Sidoo kale, xirfadlahaaga daryeelka caafimaadka ayaa laga yaabaa inuu kuu sheego siyaabaha looga hortagi karo ama loo yareeynayo qaar ka mid ah dhibaatooyinka soo raaca. Ka hubi xirfadlahaaga daryeelka caafimaad haddii mid ka mid ah waxyeelooyinka soo socda uu sii socdo ama uu ku dhibto ama haddii aad wax su'aalo ah ka qabtid:

Caan ka badan
Acid ama caloosha
xanuunka dhabarka
xayiraad
dibnaha dilaacay
shuban (khafiif)
maqaarka qalalan
madoow
sigaarka
xanuunka gacanta ama lugaha
guduudasho, barar, ama maqaar xanuun
maqaarka maqaarka iyo gacmaha iyo lugaha
nabarrada, boogaha, ama dhibco cad oo ku yaal afafka, afka, ama gudaha afka
caloolxanuun, xanaaq, ama xanuun
barar ama infakshan afka
xoqidda gacmaha iyo cagaha
hurdo xumo


Sida loo iibsado budada Lapatinib laga soo qaado AASraw

1.To nagula soo xiriir emailkayaga nidaamka weydiinta, ama skype onlinewakiil adeegga macaamiisha (CSR).
2.To nuujinta tirada iyo cinwaanka aad weydiisatay.
3.Our CSR waxay ku siin doontaa qiimaha, qiimaha bixinta, nambarka raadinta, siyaabaha gudbinta iyo taariikhda la qiyaasi karo (ETA).
4.Payment ayaa la sameeyaa, alaabtana waxaa loo diri doonaa saacadaha 12 (Si loo dalbado 10kg).
5.Gudbiyadu waxay heleen oo dhiibaan faallooyin.


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COA

COA 231277-92-2 Lapatinib budada AASRAW

HNMR

Waxaan nahay nadiifinta budada Lapatinib, budada Lapatinib ee iibka, budada Raw Lapatinib (231277-92-2) hplc = 98% | AASraw R & D Reagents

Recipes

Lapatinib Roodhada Rootiga ah:

Si aad u ogaato faahfaahinta macaamiisha (CSR) faahfaahinta, tixraacaaga.

Tixraacyada iyo xaashiyadaha alaabada

Tykerb (231277-92-2) -Kulinka dilaha naas-nuujinta

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