Lorcaserin HCL budada (1431697-94-7) hplc = 99% | Lacagta Fatahaada AASraw
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Lorcaserin HCL budada

Rating: SKU: 1431697-94-7. Category:

AASraw waxaa ku jira awoodda wax soo saar iyo karti wax-soo-saarka laga bilaabo gram ilaa nidaamka xajmiga ee Lorcaserin HCL budada (1431697-94-7), iyadoo la raacayo nidaamka CGMP iyo nidaamka xakamaynta tayada la socon karo.

Lorcaserin (1431697-94-7) budada HCL wuxuu saameeyaa calaamadaha kiimikada maskaxda ee xakameynaya rabitaanka cuntada. Kiniiniga Lorcaserin HCL wuxuu u shaqeynayaa inuu kaa caawiyo inaad dareentid cunto badan. Lorcaserin hydrochloride waxaa loo isticmaalaa cuntada iyo jimicsiga si loo daaweeyo buurnaanta. Daawada lorcaserin hydrochloride mararka qaarkood waxaa loo isticmaalaa in lagu daaweeyo cayilka oo la xidhiidha sonkorowga, kolestaroolka, ama cadaadiska dhiigga .

Product Description

 

Lorcaserin (1431697-94-7) video

 

 


 

Raw Lorcaserin (1431697-94-7) Calaamadaha asaasiga ee HCL

 

Name: Lorcaserin hydrochloride budada
CAS: 1431697-94-7
Qaaciddada Molecular: C11H15Cl2N
Miisaanka kelli: 232.1525
Dhibcaha Biyaha: 212 ° C
Kaydinta Nabadgelyada: -20 ℃
Color: budo White

 


 

Waa maxay Lorcaserin

 

Lorcaserin (CAS 1431697-94-7), oo lagu suuq-gareeyay magaca caanka ah BELVIQ, waa qaybta ugu muhiimsan waa Lorcaserin HCL budada 846589-98-8. FDA waxay ogolaatay lorcaserin HCL dadka qaba calyada (oo leh qiyaasta jirka ee jirka, ama BMI, 30 ama ka sareeya) ama kuwa culus (oo leh BMI of 27 ama ka sarreeya) iyo sidoo kale ugu yaraan hal xaalad caafimaad oo la xariira sida sida nooca sonkorowga 2, cadaadiska dhiigga sareeya ama kolestaroolka sare.

 

Maxay Lorcaserin u isticmaashaa

 

Lorcaserin HCL budada 846589-98-8, waxay ku jirtaa daroogada daroogada loo yaqaanno agotonin receptor agonists. Lorcaserin HCL waxaa la isticmaalaa iyada oo ay weheliso cunto iyo jidh-dhiska si loo daaweeyo cayilka, luminta fatahaada. Marmarka qaarkood waxaa la siiyaa daaweynta cayilka oo la xariira kolestaroolka sare, cadaadiska sare ee dhiigga, ama sonkorta type2. Laakiin Lorcaserin hydrochloride (Lorcaserin HCL) ma daaweyn doonto xaalad caafimaad oo hoose (sida cudur wadne, sonkorow, cadaadis dhiig oo sarreeya).

 

Lorcaserin ee ficilka

 

Kiniinada Lorcaserin hydrochloride waxay u shaqeysaa xakamaynta cuntada, gaar ahaan iyada oo la xoojinayo xayawaanka maskaxda ee serotonin, neurotransmitter oo kiciya dareenka fekerka iyo qanacsanaanta. Cunto qaadashada waxaa gacanta ku haya xarun faaruq ah, oo ku dhexjirta nuclejiyanka vantomedial of hypothalamus iyo xarunta gaajada ee joogtada ah ee lateral hypothalamus. Waxyeelo kala duwan oo ka yimaada xarumaha sare iyo mareenada caloosha ayaa isku dhejiya nucleus, oo laba nooc oo ah qanjirro xakameynaya cunto qaadashada. Ugu horreyn, kooxda dhiirigelinta cuntada ee soo saarida borogaraamyada ageari-la xiriira iyo neuropeptide Y; iyo marka labaad, koox cunto-qaadasho ah oo ay ka kooban tahay kookeynta iyo amphetamine-ga ("CART") iyo pro-opiomelanocortin (POMC) neurons. POMC waxaa ku jira receptors 5-HT 2C, taas oo marka firfircoon la sii daayo hormoonka alpha-melanocyte-stimulating hormone (alpha-melh) .Dhibaatooyinka nukleerka iyo naqshadaynta nukliyadaha dheeraadka ah ee ku jira hypothalamus. Nucleuserka macmalka waxaa ku jira receptors melanocyte 4 (MC4R) qiyaasaha lorcaserin waxay u dhaqmaan sidii 5-HT 2C agonist oo ku yaala maskaxda POMC, taas oo keenta in la sii daayo alfa MSH. Alpha MSH dheeraad ah waxay wax ka qabataa MC4R ee nukleerka nukleus ee hypothalamus, taasoo keentay hoos u dhaca cuntada. Daawooyinka supraterapeutic, lorcaserin waxay sidoo kale wax ka qabataa 5-HT 2B iyo 5-HT 2A.

 

Sida loo isticmaalo budada Lorcaserin HCL (CAS 1431697-94-7)

 

Budada Lorcaserin HCL waa budo cad oo ka baxsan-cad oo leh milmi biyo ka weyn 400 mg / mL. Kiniin kasta oo ah BELVIQ XR wuxuu ka kooban yahay 20.8 mg oo ah crystalline lorcaserin hydrochloride hemihydrate, oo u dhiganta 20.0 mg lorcaserin hydrochloride budada, iyo waxyaabaha soo socda ee aan firfircooneyn: microcrystalline cellulose NF; mannitol USP; hypromellose 2208 USP; kala firdhinta ethylcellulose Nooca B NF; hypromellose 2910 USP; colloidal silicon dioxide NF; polyvinyl aalkolada USP; polyetylen glycol NF; titanium dioxide USP; talc USP; FD & C huruud ah # 6 / qorrax dhaca huruud FCF; harada aluminium; birta birta ah ee huruudka ah NF; birta xabagta cas NF; iyo magnesium stearate NF.

Xuduuda Lorcaserin HCL 846589-98-8 waxay ku timaadaa qaab kiniin ah waxaana la qaataa 1-2 jeer maalintii, iyada oo aan cunto lahayn ama aan laheyn. Lorcaserin waa in loo isticimaalaa cunto yar oo kalooriye ah iyo qorshe jimicsi.

 

Isdhaafsashada Lorcaserin

 

-monamine oxidase inhibitor sida isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), Selegiline (Emsam, Eldepryl, Zelapar), rasagiline (Azilect)

(SRRI) sida safarka (Lexapro), sertraline (Zoloft), citalopram (Celexa), Paroxetine (Paxil), fluoxetine (Prozac, Sarafem), iyo fluvoxamine (Luvox)

-tricyclic antidepressants sida trimipramine (Surmontil), amitriptyline (Elavil), nortriptyline (Pamelor, Aventyl), protriptyline (Vivactil), iyo clomipramine (Anafranil)

 


 

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