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Powder-ka loo yaqaan 'Ulipristal Acetate Powder' (26784-99-4)

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AASraw waxay la jirtaa awood iyo soosaarid laga bilaabo gram ilaa amar ballaaran oo ah Ulipristal Acetate Powder (26784-99-4), oo hoos timaada qaanuunka CGMP iyo nidaamka xakamaynta tayada tayada la socon karo.

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Product Description

Muuqaalka Ulipristal Acetate Powder (26784-99-4) fiidiyow


Budada Ulipristal Acetate Powder (26784-99-4) SNadiifinta:

Qaab dhismeedka kiimikada: Product Name: Ulipristal Acetate (Ulipristal Acetate dhexdhexaad ah)
Cas No.: 26784-99-4/126690-41-3/54201-84-2
Formula kelli: C30H37NO4
Miisaanka kelli: 475.62
micne ah: 3,20-bis-Ethylenedioxy-5α,17α-dihydroxy-11β-(4-N,N-dimethylaminopheynl)-19-norpregn-9-ene; 3,20-bis-Ethylenedioxy-19-norpregna-5(10)9(11)dien-17-ol
kaydinta: Ku keydi heerkulka qolka ka fog iftiinka iyo qoyaanka.
Dukumentiyada (COA & HPLC iwm.): Waa la heli karaa

Powder Upsristal Acetate (26784-99-4) Dqorey:

Ulipristal acetate waxaa loo oggolaaday in loo isticmaalo caafimaadka gudaha Mareykanka sanadkii 2010. Waxay ku qoran tahay Liiska Daawooyinka Ururka Caafimaadka Adduunka, waa daawooyinka ugu waxtarka badan uguna nabdoon ee looga baahan yahay nidaam caafimaad. Boqortooyada Ingiriiska waxay ku kacaysaa NHS qiyaastii 17 rodolkiiba Koorsada xakameynta dhalmada ee degdegga ah ee 2015. Si loo wanaajiyo helitaanka, waxay qaarkood kugula talinayaan dhammaan kuwa uur leh in la siiyo warqad dhakhtar oo loo isticmaalo haddii loo baahdo.

Budada Ulipristal acetate waxay ka kooban tahay xulasho jihooyinka progesterone receptor modulators, ka soo horjeedka antagonistic iyo saameynta firfircoon ee receptor progesterone ah. Isaga iyo jidhka receptor-ka progesterone isku xidha si looga hortago progesterone iyo kuwa qaata progesterone-ka. Aashitada loo yaqaan 'Acetic acid' ee wax ku oolnimada waxay kuxirantahay waqtigeenna aan ku bixinno wareegga caadada. Gaarsiinta bartamaha dhegaha follicular hyperplasia ayaa laga yaabaa inay joojiso folliculogenesis waxayna yareyneysaa feejignaanta estradiol. Maamulka xakamaynta hormoonnada luteinized ee jeexjeexyada dillaaca dib-u-dhaca ee 5 ~ 9 maalmood. Corpus luteum ee maamul hore ee aan daahid cad u ahayn koriinka endometrial, laakiin wuxuu sameyn karaa yareynta dhumucda endometrial ee 0.6 ± 2.2mm (micnaheedu waa ± SD).

Tixraaca:

  • Qaaciddada qaranka ee Ingiriiska: BNF 69 (69 ed.). Ururka Caafimaadka ee Ingiriiska. 2015. pp 510, 560. ISBN 9780857111562.
  • Trussel, James; Raymond, Elizabeth G .; Cleland, Kelly (2014). "Ka Hortagga Degdegga ah: Fursadda Ugu Dambeysa ee Ka Hortagga Uurka Aan Loogu Talagelin" (PDF). Akhrinta Casriga ah ee Sharciga iyo Cadaalada Bulshada. 6 (2): 7-38. La keydiyey (PDF) asalka 23 Sebtember 2010.
  • HRA Pharma (Maarso 2013). "Wadammada loo adeegsado barnaamijka 'ellaOne' '. Paris: HRA Pharma. Waxa laga keydiyay asalka 28 Luulyo 2013. Waxaa dib loo helay 25-kii Maarso 2014.